Elizabeth Perkins

as Evelyn

as Margaret McLanden

as May / Quippy Spider-Person (voice)

as Constance

as Isabel

as Phyllis (voice)

as Melanie Cave

as Ann Moody

as Elena

as Rhonda

as Jackie O'Neill

as Diane Villa

as Birdie Howard

as Janet Malone

as Phyllis Adler (uncredited)

as Jane

as Katherine Arthurton

as Marren Trudeau

as Elaine Green

as Bonnie O'Hare

as Self - Guest

as Mrs. Langley

as Self - Guest

as Sondra Carmichael

as Celia Hodes

as Carol

as Gail Meyers

as Rachel Kleinman

as Self - Restaurant Patron

as Alcmene

as Miranda Coolidge

as Dr. Emma Temple

as Joyce Sordino

as Coral (voice)

as Blanche

as Christine Rapp

as Judy Chapman

as Mama

as Mrs. Brody

as Marilyn

as Lily Cummings

as Alice Hedley

as Alice Hedley

as Self

as Joan Blake

as Self - Guest

as Aubrey Wicker

as Marilyn Lovell

as Susan

as Gertruda Babilinska (segment "Mamusha")

as Skye Weston

as Self

as Jan Shaw (voice)

as Mrs. Ashmore (voice)

as Ruth Brown / Sherilyn (voice)

as Rebecca Trager Lott

as Dorey Walker

as Wilma Flintstone

as Jennifer Morton

as Sally Wheeler

as June

as Lorraine "Lorie" Bryer

as Ann Kaye

as Jane

as Stella Wynkowski

as Dr. Garrett

as Adie Nims

as Susan

as Jo Ann

as Joan

as Self

as Judy Chapman